🌿 Histamine Levels

A blood test measuring histamine, a chemical involved in allergic reactions and immune responses.

🔍 What is it?

Histamine is released by the body during allergic reactions causing symptoms like itching, swelling, and redness. Measuring blood histamine helps assess allergic or mast cell-related disorders.

🧪 What does it measure?

• Concentration of histamine in the blood
• May also test for related markers like tryptase (mast cell activation)

🔎 Note:

• Histamine levels fluctuate and can be affected by recent allergic reactions or medications
• Often measured alongside other allergy or mast cell tests

❓ Why might I need it?

You may be advised if you have:

• 🤧 Unexplained allergic symptoms
• 🌡️ Chronic itching, flushing, or hives
• 🤕 Suspected mast cell activation syndrome
• 🔄 Symptoms not explained by standard allergy tests

🧬 Conditions it can help detect:

• Allergic reactions
• Mast cell activation disorders
• Histamine intolerance

🩺 How is it done?

• Blood drawn from a vein, usually fasting recommended
• Sample processed quickly to avoid histamine degradation
• ⏳ Results usually in 2–5 days

💷 Typical Private Cost in the UK:
£70–£130 depending on testing laboratory

✅ Commonly Combined With:

• Total IgE and specific IgE tests
• Tryptase levels for mast cell activity
• Other allergy panels

📚 References:

• British Society for Allergy and Clinical Immunology (BSACI)
• Mast Cell Disease Society UK